Therapeutic azo-compounds for drug delivery
AssigneeRutgers, The State University of New Jersey
InventorKathryn E. Uhrich
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Abstract
Polyazo compounds, which include low molecular weight drugs having a carboxylic acid group and an amine, thiol, alcohol or phenol group within their structure, formed into polymeric drug delivery systems are provided. Also provided are methods of producing polymeric drug delivery systems having these polyazo compounds as well as methods of administering low molecular weight drugs to a host via the polymeric drug delivery systems.
Claims36
A polymer comprising a backbone, wherein the backbone comprises one or more azo linkages, and wherein the backbone comprises one or more groups that will yield a biologically active compound upon hydrolysis of the polymer.
A therapeutic method for treating inflammatory bowel disease comprising administering to a mammal in need of such therapy, an effective amount of a biocompatible and biodegradable polyanhydride having repeating units of the formula:
A polymer having repeating units of the formula:
A therapeutic method for treating inflammatory bowel disease comprising administering to a mammal in need of such therapy, an effective amount of a biocompatible and biodegradable polyanhydride having repeating units of the formula:
A polymer having repeating units of the formula:
Dependencies are inferred from the claim text.