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US 6,602,902 B2Granted
Dha-pharmaceutical agent conjugates to improve tissue selectivity
AssigneeProtarga, Inc.
InventorsVictor E. Shashoua, Charles E. Swindell, Nigel L. Webb, Matthews O. Bradley
Life of this patent
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Abstract
The invention provides conjugates of cis-docosahexaenoic acid and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
Claims8
A method for targeting a drug to a noncentral nervous system tissue to treat a noncentral nervous system condition comprising:
- administering to a subject in need of such treatment a covalent conjugate of cis-docosahexaenoic acid and a pharmaceutical agent effective for treating said noncentral nervous system condition, wherein the pharmaceutical agent is a noncentral nervous system acting agent that is nonactive within the central nervous system.
A pharmaceutical preparation comprising:
- a covalent conjugate of cis-docosahexanoic acid and a noncentral nervous system active agent, and
- a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.