Muscarinic receptor agonists
AssigneeThe University of Toledo
InventorsWilliam S. Messer, Yang Cao
Life of this patent
Estimating the term…
Abstract
A compound of Formula (III): wherein X is a linkage independently selected from (CH2)12 or (CH2CH2)4O3 and wherein R3 is independently selected from H, CH2CH3, COCH3 or and acid addition salts, solvates and hydrates thereof. The compounds have unusually high affinity for muscarinic receptors, and exhibit agonist activity useful in the treatment of neurological and other disorders, in which stimulating cholinergic activity is desirable.
Claims7
A method of treating a condition selected from pain and Alzheimer's disease comprising administering to a patient in need of such treatment a muscarinic agonistic effective amount of a compound of formula (III):
- wherein X is a linkage independently selected from (CH2)12 or (CH2CH2)4O3;
- and wherein R3 is independently selected from H, CH2CH3, COCH3 or
Dependencies are inferred from the claim text.