3-phenyl-3,7-diazabicyclo[3.3.1] nonane compounds, process for preparing them, pharmaceutical compositions containing them and use thereof to inhibit cardiac arrhythmia

A process for preparing a compound corresponding to formula I

• wherein
• R1 is an alkyl group with 1-6 carbon atoms or a cycloalkylalkyl group with 4-7 carbon atoms,
• R2 is lower alkyl, and
• R3 is lower alkyl, or
• R2 and R3 together form an alkylene chain with 3-6 carbon atoms, and
• R4 represents a phenyl radical monosubstituted in the ortho or para position by nitro, cyano or lower alkanoyl or disubstituted in the ortho and para positions by nitro,
• or a physiologically compatible acid addition salt thereof, said method comprising reacting a compound corresponding to formula II
• wherein R1, R2 and R3 have the above meanings, with a compound corresponding to formula III
• R4−X III
• wherein R4 has the above meaning and X is halogen, and optionally converting a free base of Formula I into a corresponding acid addition salt or converting an acid addition salt of a compound corresponding to formula I into the corresponding free base.