Compounds derived from benzoic acid esters, composition containing said compounds and use thereof
AssigneeL'oreal
InventorsJean-Baptiste Galey, Maria Dalko, Lionel Breton
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Abstract
This invention relates to novel compounds of formula (I) wherein R1 represents a polymer, aryl or alkyl group, R2 represents a hydrogen atom, a halogen atom, a radical CN, CF3, OH, OCF3, COOH, R7, OR7 or OCOR7, R3 represents an aryl or alkyl halogen, R4 represents an alkyl radical. The invention also relates to a cosmetic composition comprising said compounds and to the use thereof to reduce and/or curb hair loss i.e. to increase and/or stimulate the growth of said hair.
Claims37
A compound of formula (I):
- wherein:
- R1 is chosen from substituted aryl groups;
- R2 is chosen from a hydrogen atom, a halogen atom, CF3, OH, OCF3, COOH, R7, OR7, and OCOR7, wherein R7 is chosen from linear and branched (C1-C4) aliphatic alkyl groups;
- R3 is chosen from monohalogenated and polyhalogenated linear and branched (C1-C4) alkyl groups, and from aryl groups;
- and
- R4 is chosen from linear and branched (C1-C4) alkyl groups, and a CF3 group.
A compound of formula (I):
- said compound comprising at least one compound chosen from:
- 4-(O-methyloxime)phenyl ester of 2-hydroxy-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- phenyl ester of 2-hydroxy-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- methyl ester of 4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- para-tolyl ester of 2-hydroxy-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- phenyl ester of 2-hydroxy-4-(2-phenyl-2-hydroxypropionylamino)benzoic acid;
- methyl ester of 2-methoxy-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- phenyl ester of 2-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- methyl ester of 2-ethyl-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- 3,5-bis(trifluoromethyl)benzyl ester of 2-hydroxy-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionyl-amino)benzoic acid;
- tert-butyl ester of 2-hydroxy-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- 3-morpholinopropyl ester of 2-hydroxy-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- 4-octylphenyl ester of 2-hydroxy-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid;
- and
- methyl ester of 2-hydroxy-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropionylamino)benzoic acid.
A composition comprising, in a physiologically acceptable medium, at least one compound of formula (I):
- wherein:
- R1 is chosen from substituted aryl groups;
- R2 is chosen from a hydrogen atom, a halogen atom, CF3, OH, OCF3, COOH, R7, OR7, and OCOR7, wherein R7 is chosen from linear and branched (C1-C4) aliphatic alkyl groups;
- R3 is chosen from monohalogenated and polyhalogenated linear and branched (C1-C4) alkyl groups, and from aryl groups;
- and
- R4 is chosen from linear and branched (C1-C4) alkyl groups, and a CF3 group.
A cosmetic composition comprising, in a cosmetically acceptable medium, at least one compound of formula (I):
- wherein:
- R1 is chosen from substituted aryl groups;
- R2 is chosen from a hydrogen atom, a halogen atom, CF3, OH, OCF3, COOH, R7, OR7, and OCOR7, wherein R7 is chosen from linear and branched (C1-C4) aliphatic alkyl groups;
- R3 is chosen from monohalogenated and polyhalogenated linear and branched (C1-C4) alkyl groups, and from aryl groups;
- and
- R4 is chosen from linear and branched (C1-C4) alkyl groups, and a CF3 group.
A method for achieving at least one result chosen from reducing or slowing down loss of head hair and body hair, and inducing or stimulating growth of head hair and body hair, comprising,
- applying to at least one type of hair chosen from head hair and body hair a composition comprising at least one compound of formula (I):
- wherein:
- R1 is chosen from substituted aryl groups;
- R2 is chosen from a hydrogen atom, a halogen atom, CF3, OH, OCF3, COOH, R7, OR7, and OCOR7, wherein R7 is chosen from linear and branched (C1-C4) aliphatic alkyl groups;
- R3 is chosen from monohalogenated and polyhalogenated linear and branched (C1-C4) alkyl groups, and from aryl groups;
- and
- R4 is chosen from linear and branched (C1-C4) alkyl groups, and a CF3 group.
A method for cosmetically treating at least one of head hair, body hair, and the scalp, comprising:
- applying to at least one of head hair, body hair, and the scalp, a cosmetic composition comprising, in a physiologically acceptable medium, at least one compound of formula (I):
- wherein:
- R1 is chosen from substituted aryl groups;
- R2 is chosen from a hydrogen atom, a halogen atom, CF3, OH, OCF3, COOH, R7, OR7, and OCOR7, wherein R7 is chosen from linear and branched (C1-C4) aliphatic alkyl groups;
- R3 is chosen from monohalogenated and polyhalogenated linear and branched (C1-C4) alkyl groups, and from aryl groups;
- and
- R4 is chosen from linear and branched (C1-C4) alkyl groups, and a CF3 group;
- leaving the cosmetic composition in contact with the at least one of head hair, the scalp, and the body hair for a cosmetically effective amount of time, and
- rinsing the at least one of head hair, the scalp, and the body hair.
Dependencies are inferred from the claim text.