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US 6,602,507 B1Granted
Synthetic peptides from streptococcal M protein and vaccines prepared therefrom
AssigneeThe Rockefeller University
InventorVincent A. Fischetti
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Abstract
Synthetic polypeptides from the conserved exposed region of streptococcal M protein are useful to prepare vaccines for oral or intranasal administration which will protect against streptococcal infection.
Claims11
An antigen conjugate which comprises a linkable carrier covalently bound to a polypeptide which consists of five or more amino acid residues from the conserved exposed region of the M protein of group A streptococci, wherein said antigen conjugate elicits a protective immune response to streptococcal infection in a mammal when administered mucosally.
Dependencies are inferred from the claim text.