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US 6,602,492 B2Granted
Cysteine derivatives
AssigneeAjinomoto Co., Inc.
InventorsKeiji Iwasaki, Manabu Kitazawa, Eiji Shiojiri, Kazutami Sakamoto
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AssigneeAjinomoto Co., Inc.
InventorsKeiji Iwasaki, Manabu Kitazawa, Eiji Shiojiri, Kazutami Sakamoto
Estimating the term…
Objects of the present invention are to provide an oxidative stress inhibitor which is capable of suppressing the expression of a cytotoxic protein and the activation of a gene transcriptional regulatory factor taking part such expression of a cytotoxic protein and exhibits good feeling upon use and safety; to provide a method for preventing, retarding, alleviating or treating a skin change due to aging or an undesirable aesthetic skin change, both caused or promoted by an oxidative stress; and to provide a cosmetic composition or dermatologic preparation for external use comprising the oxidative stress inhibitor as an effective ingredient, and for those purposes are employed an oxidative stress inhibiting agent which comprises, as an effective ingredient, at least one selected from cysteine or cystine derivatives and the salts thereof.
A composition comprising N,N′-di(octanoyl)-L-cystine dimethyl ester and at least one of an antioxidant, an anti-inflammatory, or an ultraviolet light absorber.
A method of preventing, retarding, alleviating or treating an oxidative stress skin change in a subject comprising administering to the skin of the subject an effective amount of a composition comprising N,N′-di(octanoyl)-L-cystine dimethyl ester and a dermatological or cosemtically acceptable ingredient to prevent, retard, alleviate or treat the oxidative skin change.
A method of preventing, retarding, alleviating or treating an oxidative stress skin change in a subject comprising administering to the subject an effective amount of N,N′-di(octanoyl)-L-cystine dimethyl ester to prevent, retard, alleviate or treat the oxidative skin change.
A method of making the composition of comprising mixing N,N′-di(octanoyl)-L-cystine dimethyl ester and at least one of an antioxidant, an anti-inflammatory, or an ultraviolet light absorber.
Dependencies are inferred from the claim text.