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US 6,602,287 B1Granted
Stent with anti-thrombogenic coating
AssigneeAdvanced Cardiovascular Systems, Inc.
InventorsDeborra Sanders Millare, Steven Z-H Wu
Life of this patent
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Abstract
A glycocalyx-like material is applied to a stent in order to mimic the outer surface of the cells lining arteries and veins to prevent thrombogenesis. The glycocalyx material is applied over a base layer of a fluorocarbon that is applied directly to the stent surfaces.
Claims8
A method for preventing thrombogenesis on a surface of an implantable medical device, comprising the steps of:
- providing a medical device configured for implantation in the body;
- applying a base layer of fluorocarbon material to said medical device wherein said fluorocarbon material is selected from the group consisting of C3F8, C3F6, and C2F6;
- and
- applying a glycocalyx material to said base layer, wherein said glycocalyx material includes a water repellent side chain that attaches to said fluorocarbon material and a sugar side chain that prevents the attachment of plasma proteins thereto.
1 more element
A stent, comprising:
- an expandable structure;
- a base coating of fluorocarbon material wherein said fluorocarbon material is selected from the group consisting of C3F8, C3F6, and C2F6;
- and
- a top coating of a glycocalyx material, wherein said glycocalyx material includes a water repellent side chain that attaches to said fluorocarbon material and a sugar side chain that prevents the attachment of plasma proteins thereto.
1 more element
Dependencies are inferred from the claim text.