US 6,600,010 B2 · Biodegradable terephthalate polyester-poly (phosphate) polymers, compositions, articles, and methods for making and using the same

Abstract

Biodegradable terephthalate polymers are described comprising the recurring monomeric units shown in formula I: wherein R is a divalent organic moiety; R′ is an aliphatic, aromatic or heterocyclic residue; x is ≧1; and n is 0-5,000, wherein the biodegradable polymer is biocompatible before and upon biodegradation. Processes for preparing the polymers, compositions containing the polymers and biologically active substances, articles useful for implantation or injection into the body fabricated from the compositions, and methods for controllably releasing biologically active substances using the polymers, are also described.

Claims45

Dependent claims

A polymer composition, comprising the recurring monomeric units shown in formula I:

wherein R represents a branched or straight chain divalent aliphatic group;
R′ represents an aliphatic, aromatic or heterocyclic residue;
x is greater than or equal to about 1;
n is 1-5,000;
wherein said polymer composition is biocompatible before and upon biodegradation.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

09/921,297Filed 2 Aug 2001 · continuation

Priority

3 Apr 1997

Published

US 2002/0091230 A111 Jul 2002

Granted

29 Jul 2003

Term ends

Not estimatedThe source records don’t support an estimate.

Classification11 codes

C08G 63/6926
Derived from polycarboxylic acids and polyhydroxy compounds: dicarboxylic acids and dihydroxy compounds
A61K 9/1647
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers: polyesters, e.g. poly
A61L 17/12
Containing macromolecular materials: homopolymers or copolymers of glycolic acid or lactic acid
A61L 26/0019
Containing macromolecular materials: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

Family

Application08/832,215Parent of this continuation-in-part · filed 3 Apr 1997

Application09/053,648Parent of this continuation · filed 2 Apr 1998

US 2002/0091230 A1Pre-grant publication · published 11 Jul 2002

US 6,322,797 B1Parent of this continuation

Application09/053,648Parent of this continuation-in-part

US 6,600,010 B2This patent

From the US filing history. Foreign family members aren’t listed.

Biodegradable terephthalate polyester-poly (phosphate) polymers, compositions, articles, and methods for making and using the same

Life of this patent

Biodegradable terephthalate polyester-poly (phosphate) polymers, compositions, articles, and methods for making and using the same

Life of this patent

Abstract

Claims45