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AssigneePancosma Societe Anonyme pour l'Industrie des Produits
InventorsDenis Felisaz, Yvan Jacquier
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A masking agent for pharmaceutical tastes comprises a mixture of a sapid agent and an enhancer, in the form of an intimate mixture. The sapid agent/enhancer distribution is substantially homogeneous and non-statistical. The proportion of sapid agent relative to the enhancer is substantially constant and equal in all powder particles. The masking agent can have a grain size comprised between 10 and 100 μm, with a Gaussian distribution. The proportion of sapid agent/enhancer is comprised between 97/3 and 90/10, expressed in parts by weight. The sapid agent comprises a sweetener selected from the group comprising sodium saccharinates, calcium saccharinates, saccharine, aspartyl-phenylalanine, acesulfam, cyclamates, stevioside, and mixtures thereof; and the enhancer is selected from the group comprising thaumatin, neohesperidin dihydrochalcone (NHDC), glycyrrhizin, and mixtures thereof. A method of producing a masking agent is also disclosed.
A masking agent for pharmaceutical tastes, comprising a mixture of a sapid agent and an enhancer, in the form of an intimate mixture wherein the sapid agent/enhancer distribution is substantially homogeneous, non-statistical, and wherein the portion of sapid agent relative to the enhancer is substantially constant and equal in all powder particles, and wherein the sapid agent is drawn from a class that includes sweeteners including methyl-, ethyl- and carboxyl(m)ethyl celluloses, pectins, carraghenates, alginates, sodium and calcium saccharinates, saccharine, aspartylphenylalanine, aspartam, acesulfams, acesulfam K cyclamates, steviosides, and mixtures thereof, and the enhancer is drawn from a class that includes proteins of vegetable origin, thaumatin, glycosides, neohesperidin dihydrochalcone (NHDC), glycyrrhizin, maltols, ethyl maltol glutamates, and mixtures thereof.
A medicament in powder form, comprising in the form of an intimate mixture wherein the sapid agent/enhancer distribution is substantially homogenous, non-statistical, and wherein the proportion of sapid agent relative to the enhancer is substantially constant and equal in all powder particles, and wherein the sapid agent is drawn from a class that includes sweetners including methyl-, ethyl- and carboxy(m)methyl celluloses, pectins, carraghenates, alignates, sodium and calcium saccharinates, saccharine, aspartylphenylalanine, aspartam, acesulfams, acesulfam K cyclamates, steviosides, and mixtures thereof, and the enhancer is drawn from a class that includes protiens of vegetable origin, thaumatin, glycosides, neohesperidin dihydrochalcone (NHDC), glycyrrhizin, maltols, ethyl maltol glutamates, and mixtures thereof.
A masking agent for pharmaceutical tastes, comprising a mixture of a sapid agent and a potentiator, in the form of an intimate mixture whereof the sapid agent/potentiator distribution is substantially homogeneous, non-statistical, and wherein the proportion of sapid agent relative to the potentiator is substantially constant and equal in all powder particles, said masking agent having a grain size comprised between 10 and 100 m with a Gaussian distribution, and wherein the sapid agent is drawn from a class that includes sweeteners including methyl-, ethyl- and carboxyl(m)ethyl celluloses, pectins, carraghenates, alginates, saccharinates, saccharine, aspartyiphenylalanifle, aspartam, acesulfams, acesulfam K cyclamates, steviosides, and mixtures thereof, and the enhancer is drawn from a class that includes proteins of vegetable origin, thaumatin, glycosides, neohesperidin dihydrochalcone (NHDC), glycyrrhizin, maltols, ethyl maltol glutamates, and mixtures thereof.
Dependencies are inferred from the claim text.