Homogenous water-free formulations containing glycerophospholipids and polar or lipophilic substances, method for the production thereof

A method of producing a homogeneous, anhydrous powder, the powder including as component as component (A) at least one glycerophospholipid;

• as component (B) at least one substance showing an affinity with glycerophospholipids selected from the group consisting of polar and lipophilic substances;
• wherein said component (A) and said component (B) are present in a molar ratio of 1:0.001 to 1:2;
• and optionally as component (C) a formulation aid comprising at least one anhydrous liquid C2 to C4 compound having at least two hydroxyl groups;
• wherein said component (A) and said component (C) are present in a molar ratio of from 1:0.001 to 1:1;
• said method consisting essentially of the steps of:
• (a) dissolving component (B) in at least one liquid selected from the group consisting of 1) an anhydrous solvent and 2) component (C);
• (b) dissolving glycerophospholipid component (A) in at least one solvent selected from the group consisting of an anhydrous solvent and an anhydrous solvent containing the formulation aid component (C);
• (c) combining the liquids from steps (a) and (b), wherein the dissolved state of said components in the resulting solution is maintained, and
• (d) subjecting the solution from method step (c) to a fluid/fluid phase extraction process to remove the solvents and produce the anhydrous, homogeneous powder, wherein, if formulation aid (C) is present, glycerophospholipid (A) and said formulation aid (C) are present in said powder in a molar ratio of from 1:0.001 to 1:1.