Malleable implant containing solid element that resorbs or fractures to provide access channels

An implant for implantation into an implant site of living tissue comprising:

• a biocompatible, hardened implant material;
• and
• a non-particulate, bioresorbable, solid element having a greater resorption rate in vivo than the hardened implant material, or the element comprising a mechanically weak material susceptible to fracturing under force at the implant site resulting in channels or cracks, at least a portion of the element being contained in the interior of the hardened implant material, for providing macroscopic access into the interior of the hardened implant material to cells of the living tissue by the element more rapidly resorbing in vivo than the hardened implant material, or the element fracturing under force at the implant site to produce channels or cracks.

A kit for applying an implant into an implant site of living tissue comprising:

• a powder for use in preparing a paste implant material;
• and
• a non-particulate, bioresorbable solid element insertable into the paste implant material, said element having a greater resorption rate in vivo than the implanted paste implant material, or the element comprising a mechanically weak material susceptible to fracturing under force at the implant site resulting in channels or cracks, and said element providing macroscopic access into the interior of the implant to cells of the living tissue by the element more rapidly resorbing in vivo than the implanted paste implant material, or the element fracturing under force at the implant site to produce channels or cracks.

A method of making an implant and implanting the implant into an implant site of a host, comprising:

• implanting a malleable implant material into an implant site of a host, wherein said malleable implant material is capable of being deformed under pressure required to insert the malleable implant material into the implant site;
• and,
• before or after implanting said malleable implant material, introducing a non-particulate, bioresorbable solid element into the malleable implant material for providing macroscopic access into the interior of the implant to cells of the host, wherein said macroscopic access results from said element more rapidly resorbing in vivo than the implanted malleable implant material, or the element comprising a mechanically weak material and fracturing under force at the implant site to produce channels or cracks.