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US 6,597,932 B2Granted
Generation of spatially-averaged excitation-emission map in heterogeneous tissue
AssigneeArgose, Inc.
InventorsWei Dong Tian, Pierre Trepagnier
Life of this patent
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Abstract
An instrument for evaluating fluorescence of a heterogeneous tissue includes means for exciting a two-dimensional portion of the tissue surface with excitation radiation at a plurality of excitation wavelengths, means for collecting emission radiation from the two-dimensional portion of the tissue surface simultaneously with excitation of the portion, and means for forming a two-dimensional excitation-emission map of the excitation radiation and the simultaneously collected emission radiation and spatially averaging the excitation and emission radiation.
Claims8
A common fiber optic head, comprising:
- a plurality of excitation fiber optic bundles, wherein each of the plurality of excitation fiber optic bundles comprises at least twenty excitation fibers;
- a plurality of emission fiber optic bundles, wherein each of the plurality of emission fiber optic bundles comprises at least twenty emission fibers;
- and
- wherein distal ends of the excitation and emission fiber optic bundles are disposed in a two-dimensional array.
1 more element
A system comprising:
- a common fiber optic head, an excitation radiation source, and an emission radiation detector, wherein the common fiber optic head further comprises a plurality of excitation fiber optic bundles each of which comprises at least twenty excitation fibers;
- a plurality of emission fiber optic bundles each which comprises at least twenty emission fibers;
- and wherein distal ends of the excitation and emission fiber optic bundles are disposed in a two-dimensional array.
Dependencies are inferred from the claim text.