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US 6,596,861 B1Granted
Method for the reductive amination of polysaccharides
AssigneeAventis Pasteur Limited
InventorMonique Moreau
Life of this patent
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Abstract
The invention relates to a method for reductive amination of polysaccharides which comprises subjecting a reaction mixture comprising a polysaccharide, an amino compound and a reducing agent, to microwave radiation for a period of time sufficient to aminate the polysaccharide.
Claims18
A method of reductive amination of polysaccharides that comprises:
- (i) subjecting a reaction mixture comprising a polysaccharide, an amino compound and a reducing agent, to microwave radiation for a period of time sufficient to aminate the polysaccharide;
- (ii) (a) subjecting a reaction mixture comprising a polysaccharide and an amino compound to microwave radiation for a period of time sufficient to allow the formation of an imine compound, (b) adding a reducing agent to the reaction mixture obtained in (a) so that the polysaccharide is aminated;
- (iii) (a) adding an amino compound to a polysaccharide so that an imine compound is formed, (b) adding a reducing agent to the reaction mixture obtained in (a) and, (c) subjecting the reaction mixture obtained in (b) to microwave radiation for a period of time sufficient to aminate the polysaccharide;
- or
- (iv) (a) subjecting a reaction mixture comprising a polysaccharide and an amino compound to microwave radiation for a period of time sufficient to allow the formation of an imine compound, (b) adding a reducing agent to the reaction mixture obtained in (a) and, (c) subjecting the reaction mixture obtained in (b) to microwave radiation for a period of time sufficient to aminate the polysaccharide.
2 more elements
Dependencies are inferred from the claim text.