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AssigneeBecton, Dickinson and Company
InventorsKevin George Hetzler, Thea Lubrecht
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A medical transfer or storage device for delivery or storage of a medicament, drug or vaccine, wherein a first component, preferably the major component, is formed of a cyclic olefin polymer, and a second component in contact with the first component is formed of a second polymer which does not chemically interact with the cyclic olefin polymeric component at elevated temperatures, including sterilization. More specifically, the relative energy distance Ra/Ro of the polymer selected for the second component relative to the cyclic olefin polymer is greater than 0.75 and the molecular weight of the second polymer is at least 5,000 to prevent adhesion of the second component to the cyclic olefin component and stress cracking at elevated temperatures. The most preferred embodiment is a syringe assembly having a cyclic olefin polymeric barrel and a resilient stopper formed of the second polymer.
A sterilizable transfer or storage device for delivery or storage of a medicament, drug or vaccine, comprising a first member formed of a cyclic olefin polymer and a second member having a surface in contact with said first member formed of a second polymer, wherein the relative energy distance Ra/Ro of said second polymer relative to said cyclic olefin polymer is greater than 0.75 to prevent adhesion of said second member to said first member and stress cracking of said first member at elevated temperatures, including autoclaving.
A sterilizable syringe assembly including a generally tubular syringe body formed of a cyclic olefin polymer and a plunger having a stopper telescopically received in said syringe body in contact with an internal surface of said syringe body, said stopper formed of a second polymer wherein the relative energy distance Ra/Ro of said second polymer relative to said cyclic olefin polymer is greater than 0.75 to prevent adhesion of said stopper to said syringe body and stress cracking of said syringe body at the elevated sterilization temperature.
A method of making a sterilized syringe assembly comprising the following steps:
Dependencies are inferred from the claim text.