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US 6,586,585 B1Granted
Method for the size reduction of high-molecular structures
AssigneeQiagen GmbH
InventorHelge Bastian
Life of this patent
Estimating the term…
Abstract
A method for the size reduction of high-molecular structures, in particular high-molecular nucleic acid structures, in samples wherein the high-molecular structures to be size-reduced are passed through a means provided with at least one porous layer the pore size of which decreases in the direction of the passage of the structures to be size-reduced through the porous layer.
Claims9
A method for isolating nucleic acid structures from a sample, comprising
- passing a sample of polyacrylamide gel through a device, said device including means having at least one porous layer, the pore size of which decreases, in the direction of the passage of the sample through the porous layer, whereby said nucleic acid structures are reduced in size and extracted from other materials in the sample in a resulting filtrate, said filtrate having a viscosity lower than said sample, and
- processing said filtrate having a lower viscosity.
Dependencies are inferred from the claim text.