Endometriosis-associated gene
AssigneeAnna Starzinski-Powitz
InventorsAnna Starzinski-Powitz, Kotzian Silvia, Heike Handrow-Metzmacher
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Abstract
The invention relates to a gene associated with invasive processes, e.g. endometriosis, to a polypeptide coded by said gene, to an antibody directed against the polypeptide, and to the pharmaceutical application of the nucleic acid, the polypeptide and the antibody.
Claims6
A polypeptide associated with invasive processes in endometriosis, wherein said polypeptide is encoded by a nucleic acid comprising
- (a) the nucleotide sequences depicted in SEQ ID NO:1, 3 or/and 5, a combination or a protein-encoding segment thereof,
- (b) a nucleotide sequence corresponding to the sequence in (a) within the scope of the degeneracy of the genetic code, or
- (c) a nucleotide sequence hybridizing with the sequences in (a) and/or (b) under stringent conditions of washing for one hour with 1×SSC and 0.1% SDS at 50° C.,
- wherein the polypeptide encoded by the nucleic acid comprising the nucleotide sequence depicted in SEQ ID NO:1 or 3 in (a) is substantially isolated.
A polypeptide associated with invasive processes in endometriosis, said polypeptide comprising
- (a) an amino acid sequence depicted in SEQ ID NO:
- 2 or 4, or
- (b) a homology of more than 90% to the amino acid sequence according to (a),
- wherein the polypeptide in (a) is substantially isolated.
A peptide comprising a segment of at least 10 amino acids of the amino acid sequence depicted in SEQ ID NO:
- 2 or 4.
Dependencies are inferred from the claim text.