Methods for the treatment of nephro-disorders using aminothiol compounds
AssigneeMedImmune Oncology, Inc.
InventorsMartin Stogniew, David S. Alberts, Edward H. Kaplan
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Abstract
The present invention relates to new uses of S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate, (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by therapeutic agents, radiation treatment or diabetes. In particular, the invention provides a method for treating neurotoxicity and nephrotoxicity associated with the administration of chemotherapeutic agents.
Claims19
A method for treating a nephro-disorders in a human which comprises administering a therapeutically effective amount of one or more aminothiol compounds, or a pharmaceutically acceptable salt thereof, to a human in need of such treatment after the occurrence of said nephro-disorders.
Dependencies are inferred from the claim text.