Combined preparations comprising morpholine anthracyclines and anticancer agent
AssigneePharmacia Italia S.p.A.
InventorsMaria Cristina Geroni, Marina Ripamonti, Michele Caruso, Antonino Suarato
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Abstract
The present invention relates to combined preparations comprising a morpholinyl anthracycline administered in combination anticancer agents chosen from an alkylating agent, an antimetabolite, a topoisomerase II inihbitor, a topoisomerase I inhibitor, an antimitotic drug and a platinum derivative, which are useful anticancer therapy, particularly in the treatment of a primary or metastatic liver cancer.
Claims22
A synergistic anticancer combined preparation, wherein the cancer is sensitive to the synergistic combination, which comprises a morpholinyl anthracycline of formula (I)
- and an anticancer agent selected from the group consisting of an alkylating agent, an antimetabolite, a topoisomerase II inhibitor, a topoisomerase I inhibitor and an antimitotic drug.
Dependencies are inferred from the claim text.