Pharmaceutical preparations of glutathione and methods of administration thereof
AssigneeAntioxidant Pharmaceuticals Corp.
InventorsHarry B. Demopolos, Myron L. Seligman
Life of this patent
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Abstract
A method for the administration of glutathione orally comprising the administration of a bolus of glutathione which is pharmaceutically stabilized and encapsulated. The glutathione is administered on an empty stomach. The preferred stabilizer is ascorbic acid.
Claims33
A pharmaceutical formulation in orally administrable dosage form, comprising:
- (a) glutathione or a pharmaceutically acceptable salt or derivative thereof in an amount equivalent to at least 50 mg per dose;
- and
- (b) a pharmaceutically acceptable sacrificial antioxidant present in such amount and form to maintain a bulk of said glutathione in non-oxidized form;
- and
- (c) a composition selected from the group consisting of one or more of:
- an antibiotic;
- and a physiologic nitric oxide precursor.
A pharmaceutical formulation in trans-mucous membrane administrable form, comprising glutathione or a pharmaceutically acceptable salt or derivative thereof, said glutathione being maintained in non-oxidized form prior to administration by one or more of chemical and physical means.
Dependencies are inferred from the claim text.