Capillary having coated inner wall
AssigneeEisai Co., Ltd.
InventorsHiroyuki Katayama, Yasushi Ishihama
Life of this patent
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Abstract
It is to provide a capillary having adsorbed a polymer. A capillary having absorbed on an inner wall of the capillary, an ionic polymer having positive electric charge and an ionic polymer having negative electric charge alternately, and a process for producing the same.
Claims11
An electrophoresis capillary comprising (A) an ionic polymer layer selected from the group consisting of polybrene, chitosan and diethylaminoethyldextran and (B) a negatively charged ionic polymer layer selected from the group consisting of dextran sulfate, heparin, heparin sulfate, hyaluronic acid, chondroitin sulfate, keratan sulfate, polygalacturonic acid, arginic acid and teikronic acid, wherein said (A) ionic polymer layer is adsorbed on an inner wall of said capillary tubing and said (B) negatively charged ionic polymer layer is coated on said (A) ionic polymer layer to form an innermost wall of the capillary.
A method of conducting capillary electrophoresis which comprises conducting electrophoresis with a capillary having absorbed on an inner wall of the capillary, a first layer of an ionic polymer having positive electric charge selected from the group consisting of polybrene, chitosan or diethylaminoethyldextran, and a second layer of an ionic polymer having negative electric charge selected from the group consisting of dextran sulfate, heparin, heparin sulfate, hyaluronic acid, chondroitin sulfate, keratan sulfate, polygalacturonic acid, arginic acid or teikronic acid, alternately, wherein the first layer is coated on the second layer or the second layer is coated on the first layer.
Dependencies are inferred from the claim text.