Back to results
US 6,582,930 B1Granted
Porphyrin compounds, their conjugates and assay methods based on the use of said conjugates
AssigneeArctic Diagnostics Oy
InventorsGelii Vasilevich Ponomarev, Dmitry Vladimirovich Yashunsky, Niko Jarmo Juhani Meltola, Aleksi Elias Soini
Life of this patent
Estimating the term…
Abstract
The preparation of phosphorescent metalloporphyrin labelling reagents and their use for preparation of phosphorescent conjugates with biomolecules. The labelling reagents obtainable are water soluble monofunctional derivatives of Pt- and Pd-coproporphyrins, where the term “monofunctional” refers to the number of reactive groups in the porphyrin moiety.
Claims13
A substantially pure compound of formula (I) or (II):
- wherein
- M is palladium (II) or platinum (II);
- R1 is —OH, —O−X+ or —OR;
- where R is an alkyl, an aryl, an alkyaryl group or an aralkyl group and X+ is a cation
- R2 is —Y—Z, wherein
- Y is either a covalent bond, a straight or branched chain alkylene, an arylene, an alkarylene or an aralkylene group, and may contain heteroatoms or side chains containing heteroatoms, or Y is a residue of a polypeptide, polysaccharide, polynucleotide or a polyether, and Z is a functional group selected from the group consisting of isothiocyanato and maleimido.
3 more elements
Dependencies are inferred from the claim text.