Oligonucleotides
AssigneeAffymetrix, Inc.
InventorsStephen P.A. Fodor, Dennis W. Solas, William J. Dower, Xiaohua C. Huang
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Abstract
The present invention provides a number of oligonucleotide sequences which can be used for a wide variety of analyses applicable to the diverse fields impacted by the nature of molecular interaction, including chemistry, biology, medicine, and medical diagnostics. In certain embodiments these oligonucleotides may be used as probes to be used in, for example, gene expression analysis.
Claims12
A nucleic acid array comprising at least 70% of all possible, different oligonucleotide sequences, wherein the different sequence lengths are 30 mers long, are on a solid support and are present at a density of at least 1,000 per cm2.
A nucleic acid array comprising at least 70% of 4n unique oligonucleotide sequences of a given length n wherein n is 30 and wherein said array is formed on a substrate with a surface having an array of at least 1,000 distinct oligonucleotides in a surface area of 1 cm2, each distinct oligonucleotide being disposed at a separate, defined position in said array.
Dependencies are inferred from the claim text.