Compositions and methods for promoting wound healing
AssigneesUniv. of Colorado - Colorado Springs, MedLogic Global Corporation, Anodose Dermal Product, Inc.
InventorsMartha K. Newell, Ian Askill, Javin Pierce, William Crisp
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Abstract
The present invention provides methods and compositions for promoting wound healing and reducing scar formation. In particular, the present invention provides cyanoacrylate polymer sealants formulated to contain biologically active elemental silver and/or insulin. The invention also provides methods and compositions for delivering silver and/or insulin in combination with cyanoacrylate sealants. In particular, the present invention provides methods and compositions suitable for treatment of wounds in diabetics, normal patients and surgical patients.
Claims29
A method for enhancing wound healing, comprising:
- administering to a wound an effective amount for enhancing wound healing of a cyanoacrylate polymer sealant and silver, wherein the silver is a silver mesh.
A method for enhancing wound healing, comprising:
- administering to a wound an effective amount for enhancing wound healing of a cyanoacrylate polymer sealant and silver, wherein the silver is silver sutures.
A method for enhancing wound healing, comprising:
- administering to a wound an effective amount for enhancing wound healing of a cyanoacrylate polymer sealant and silver, further comprising applying a current across the silver to enhance flow into the wound.
A composition, comprising:
- a cyanoacrylate polymer sealant and insulin, the insulin incorporated within the cyanoacrylate polymer sealant, and wherein at least 50% of the insulin is biologically active.
A method for reducing scar formation, comprising:
- administering to a wound a cyanoacrylate polymer sealant and a compound selected from the group consisting of insulin and silver, wherein the combination of the sealant and the insulin or silver results in a synergistic reduction in scar formation.
A method for enhancing wound healing, comprising:
- administering to a wound an effective amount for enhancing wound healing of a cyanoacrylate polymer sealant and silver, wherein insulin is incorporated into the cyanoacrylate polymer sealant.
A method for enhancing wound healing, comprising:
- administering to a wound an effective amount for enhancing wound healing of a cyanoacrylate polymer sealant and silver, further comprising contacting the wound with insulin.
Dependencies are inferred from the claim text.