Isolated nucleotide sequences associated with multiple sclerosis or rheumatoid arthritis and a process of detecting
AssigneeBio Merieux
InventorsHerve Perron, Frederic Beseme, Frederic Bedin, Glaucia Paranhos-Baccala, Florence Komurian-Pradel, Colette Jolivet-Reynaud, Bernard Mandrand
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Abstract
The invention provides viral material and nucleotide fragments associated with multiple sclerosis and/or rheumatoid arthritis for use in methods of diagnosis, prophylaxis, and therapy.
Claims5
An isolated or purified nucleic acid selected from a group consisting of SEQ ID NO:
- 87 or its complementary sequence.
An isolated or purified nucleic acid selected from a group consisting of SEQ ID NO:
- 88 or its complementary sequence.
An isolated or purified nucleic acid coding for a peptide sequence encoded by SEQ ID NO:
- 87, SEQ ID NO:
- 88, or their complementary sequences.
A process for detecting, in a biological sample, a virus associated with multiple sclerosis or rheumatoid arthritis, comprising:
- contacting a probe to said biological sample under stringent conditions at which said probe hybridizes to a nucleotide sequence selected from the group consisting of SEQ ID NO:
- 87, SEQ ID NO:
- 88 and their complementary sequences;
- and
- determining whether the probe hybridizes with nucleic material in the biological sample, wherein hybridization indicates the presence of said virus.
Dependencies are inferred from the claim text.