Carrier particles for use in dry powder inhalers
AssigneeVectura Limited
InventorJohn Nicholas Staniforth
Life of this patent
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Abstract
In a method of producing particles suitable for use as carrier particles in dry powder inhalers, particles (1) of a size suitable for use as carrier particles in dry powder inhalers are treated so as to dislodge small grains from the surface of the particles, without substantially changing the size of the particles during the treatment. The treatment gives improved efficiency of redispersion of active particles from the surfaces of carrier particles.
Claims42
A method of producing carrier particles for use in dry powder inhalers, comprising:
- milling particles, wherein milling dislodges small grains from the surfaces of said particles, wherein said milling does not substantially change the size of said particles, and wherein said particles to be milled are of a size suitable for use as carrier particles in dry powder inhalers.
A method of producing a dry powder for use in dry powder inhalers, comprising
- milling carrier particles, wherein milling dislodges small grains from the surfaces of said carrier particles wherein said milling does not substantially change the size of said carrier particles;
- and
- mixing said milled carrier particles with active particles such that active particles adhere to the surfaces of said carrier particles.
Particles suitable for use as carrier particles in a dry powder inhaler, the particles consisting of small grains and large particles wherein the small grains are attached to the surfaces of the large particles.
Dependencies are inferred from the claim text.