Method of cleaning and priming dialysis system

A method of cleaning and priming a dialysis system where the dialysis system comprises

• a dialyzer having a dialysate flow path and a blood flow path partitioned by a dialysis membrane;
• a closed-type water-removal control apparatus for controlling a difference between volumes of a fresh dialysate flowing into the dialyzer and a used dialysate flowing out of the dialyzer by removing a volume of water, said closed-type water-removal control apparatus including a fresh dialysate chamber and a used dialysate chamber;
• a water supply line extending from a source of water to the fresh dialysate chamber;
• a dialysate line connecting the closed-type water-removal control apparatus and a dialysate flow path of the dialyzer, said dialysate line including an inlet line to the dialyzer connected to the fresh dialysate chamber and an outlet line from the dialyzer connected to the used dialysate chamber;
• a water pressurizing line connected to said water supply line at a junction with said water supply line and connected to said outlet line from the dialyzer at a junction with said outlet line from the dialyzer;
• a water pressurizing pump provided in the water pressurizing line between said junctions;
• an artery side blood line connected to a blood inlet of the dialyzer;
• a blood pump provided in the artery side blood line;
• and
• a vein side blood line connected to a blood outlet of the dialyzer;
• said method comprising pressurizing water into said dialysate line via said water pressurizing line downstream from the dialyzer to cause the dialysate to flow through the dialysis membrane of the dialyser into the blood flow path.