Amperometric biomimetic enzyme sensors based on modified cyclodextrin as electrocatalysts
AssigneeThe United States of America as represented by the Department of Health and Human Services
InventorEllen T. Chen
Life of this patent
Estimating the term…
Abstract
The present invention provides a novel biosensor for the detection of chemicals of interest. The novel biosensor of the present invention comprises an electrode having a catalytically active cyclodextrin attached thereto. The present invention will be useful for the detection of materials in a wide variety of samples. In particular, the present invention will permit the detection of nitrophenyl esters.
Claims31
A sensor comprising:
- an electrode;
- and
- a cyclodextrin chemically modified to be electrocatalytically active affixed to said electrode.
A method of detecting a material in a sample, comprising the steps of:
- obtaining a sample which can be detected;
- contacting the sample with a sensor, the sensor comprising an electrode having a cyclodextrin chemically modified to be electrocatalytically active attached thereto;
- and
- detecting the material.
A method of detecting the presence or absence of a nitrophenyl ester in a sample, comprising the steps of:
- obtaining a sample;
- contacting the sample with a biosensor, wherein the biosensor comprises a cyclodextrin chemically modified to be electrocatalytically active and an electrode;
- and
- determining the presence or absence of the nitrophenyl ester in the sample.
A method of constructing a biosensor, comprising the steps of:
- providing an electrode;
- contacting the electrode with a solution, wherein the solution comprises a cyclodextrin chemically modified to be electrocatalytically active;
- and
- affixing the electrocatalytically active cyclodextrin to the electrode.
A sensor for detecting a phenyl ester comprising:
- an electrode;
- and
- a cyclodextrin chemically modified to be electrocatalytically active.
Dependencies are inferred from the claim text.