Minocycline-containing compositions
AssigneeShowa Yakuhin Kako Co., Ltd.
InventorsKazuhiro Ono, Hidenari Sakaguchi, Ikuto Hayakawa
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Abstract
An object of the present invention is to provide a stable pharmaceutical composition for topical administration comprising minocycline as an active ingredient. According to the present invention, there is provided a pharmaceutical composition for topical administration comprising minocycline or a physiologically acceptable salt thereof in an oleaginous base.
Claims14
A pharmaceutical composition comprising:
- 0.01-15% by weight of minocycline or a physiologically acceptable salt thereof;
- 20-97% % by weight of an oleaginous base;
- 1-60% by weight of an adhesive agent;
- and,
- 1-20% by weight of a sucrose fatty acid ester.
A method for at least one of treatment and prevention of dental diseases comprising topically administering to a patient a pharmaceutical composition comprising minocycline or a physiologically acceptable salt thereof, an oleaginous base and a sucrose fatty acid ester.
A method of stabilizing a minocycline or a physiologically acceptable salt thereof comprising combining the minocycline or a physiologically acceptable salt thereof with an oleaginous base and a sucrose fatty acid ester.
Dependencies are inferred from the claim text.