Particular agents
AssigneeSyngenix Limited
InventorAaron Gershon Filler
Life of this patent
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Abstract
A novel means of pharmaceutical delivery for therapy or prophylaxis or to assist surgical or diagnostic operations on the living body is provided by agents which undergo neuronal endocytosis and axonal transport following pharmaceutical administration into vascularized, peripherally innervated tissue, e.g., intramuscular injections of a nerve adhesion molecule comprising a physiologically active substance or a diagnostic marker.
Claims48
A pharmaceutical agent comprising a nerve adhesion molecule coupled to a particulate, physiologically active substance, wherein said agent, when contacted with a nerve terminus in a vascularized, peripherally innervated tissue site or in a tissue site innervated by a spinal root, undergoes axonal transport following neuronal endocytosis.
Dependencies are inferred from the claim text.