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US 6,558,676 B1Granted
Parvovirus capsids
AssigneeThe United States of America as represented by the Department of Health and Human Services
InventorsNeal S. Young, Sachiko Kajigaya, Shimada Takashi
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Abstract
The present invention relates to a method of producing non-infections parvovirus capsids and to diagnostic assays and vaccines utilizing same. The invention further relates to recombinant baculoviruses encoding parvovirus structural proteins and host cells infected therewith. The invention also relates to a method of packaging and delivering genetic information utilizing the noninfectious capsids.
Claims2
A method of producing antibodies to B19 parvovirus capsids comprising:
- immunizing a mammal with a non-infectious empty B19 parvovirus capsid comprising a full length VP2;
- and
- isolating the antibodies produced in the mammal.
Dependencies are inferred from the claim text.