Growth differentiation factor promoter and uses therefor
AssigneeMetamorphix, Inc.
InventorLi-fang Liang
Life of this patent
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Abstract
GDF promoters (e.g., GDF-8 promoters) are described. Also described are methods of using the GDF promoters to regulate tissue-specific gene expression, and to identify compounds which regulate GDF expression.
Claims14
An isolated GDF gene promoter comprising the nucleotide sequence of SEQ ID NO:1.
An isolated GDF gene promoter comprising the nucleotide sequence of SEQ ID NO:2.
An isolated GDF gene promoter comprising the nucleotide sequence of SEQ ID NO:3.
An isolated GDF gene promoter consisting of the nucleotide sequence of SEQ ID NO:1.
An isolated GDF gene promoter consisting of the nucleotide sequence of SEQ ID NO:2.
An isolated GDF gene promoter consisting of the nucleotide sequence of SEQ ID NO:3.
An isolated GDF gene promoter comprising a nucleotide sequence which is at least 95% identical to the entire nucleotide sequence of SEQ ID NO:1.
An isolated GDF gene promoter comprising a nucleotide sequence which is at least 90% identical to the entire nucleotide sequence of SEQ ID NO:1.
An isolated GDF gene promoter comprising a nucleotide sequence which is at least 98% identical to the entire nucleotide sequence of SEQ ID NO:1.
Dependencies are inferred from the claim text.