Antibodies to natural killer stimulatory factor
AssigneesWyeth, The Wistar Institute
InventorsGiorgio Trinchieri, Bice Perussia, Steven C. Clark, Gordon G. Wong, Rodney Hewick, Michiko Kobayashi
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Abstract
This application relates to antibodies reactive with a novel homogenous human cytokine, Natural Killer Stimulator Factor (NKSF), having the ability to induce the production of gamma interferon in vitro in human peripheral blood lymphocytes, and a pharmaceutical preparation containing such antibodies.
Claims4
A monoclonal antibody which specifically reacts with natural killer cell stimulatory factor (NKSF) protein, wherein said protein has (a) a first subunit comprising the amino acid sequence of FIG. 1 from amino acids 23 to 328, and (b) a second subunit comprising the amino acid sequence of FIG. 2 from amino acid 57 to 253.
Dependencies are inferred from the claim text.