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US 6,555,652 B1Granted
Tumor antigen peptide derivatives
AssigneeKyogo Itoh
InventorsKyogo Itoh, Shigeki Shichijo, Yasuhisa Imai
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Abstract
Tumor antigen peptide derivatives which comprise all or part of an amino acid sequence derived from the amino acid sequence shown in SEQ ID NO: 3 through the alteration of one to several amino acid residues, which are capable of binding to HLA-A24 antigen and thus being recognized by cytotoxic T cells; the use of these tumor antigen peptide derivatives in treating, preventing and diagnosing tumors; and remedies or preventives for tumors containing these peptide derivatives as an active ingredient.
Claims7
A tumor antigen peptide derivative which comprises the amino acid sequence of SEQ ID No:
- 3, wherein the amino acid residue at the second and/or the ninth position of SEQ ID No:
- 3 are substitued with another amino acid residue, which derivative binds HLA-A24 such that the derivative is recognized by cytotoxic T cells.
Dependencies are inferred from the claim text.