Physically crosslinked amphiphilic networks, methods of preparation, and uses thereof
AssigneeThe University of Akron
InventorsJoseph P. Kennedy, Pious Kurian
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Abstract
The present invention relates to amphiphilic copolymer networks comprising polyisobutylene segments and poly(alkylene glycol) segments. The polyisobutylene segments of the amphiphilic networks are physically crosslinked by hydrophobic forces. The amphiphilic networks have particular use as coatings for biological implants. Also provided is a process for preparing a physically crosslinked amphiphilic copolymer network comprising: providing a block copolymer comprising polyisobutylene segments and poly(alkylene glycol) segments; introducing the block copolymer into an aqueous solvent; and allowing the block copolymer to self-assemble into physically crosslinked a copolymer network.
Claims18
A physically crosslinked amphiphilic copolymer network comprising a linear block copolymer having hydrophobic polyisobutylene segments and hydrophilic poly(alkylene glycol) segments, wherein the block copolymer has been prepared by hydrosilation, and wherein said polyisobutylene segments are physically crosslinked by hydrophobic forces when said block copolymer is placed in an aqueous media.
A process for preparing a physically crosslinked amphiphilic copolymer network comprising:
- providing a linear block copolymer comprising polyisobutylene segments and poly(alkylene glycol) segments, wherein the block copolymer has been prepared by hydrosilation;
- introducing the block copolymer into an aqueous solvent;
- and
- allowing the block copolymer to self-assemble into a physically crosslinked copolymer network.
Dependencies are inferred from the claim text.