Compounds with growth hormone releasing properties

A compound of formula I

• wherein
• R1 is hydrogen or C1-6-alkyl optionally substituted with aryl;
• R2 is C1-6-alkyl optionally substituted with aryl;
• a and b are independently 1 or 2;
• G is —O—(CH2)k—R27,
• J is —O—(CH2)l—R32,
• wherein
• R27, R28, R29, R30, R31, R32, R33, R34, R35 and R36 are hydrogen, halogen, aryl ,C1-6-alkyl or C1-6-alkoxy;
• k and l are independently 0, 1 or 2;
• D is
• R7—NH—(CR8R9)p−(CH2)m—M—(CHR10)o—(CH2)n—
• wherein
• R7, R8, R9 and R10 are independently hydrogen or C1-6 alkyl optionally substituted with halogen, amino, hydroxyl or aryl;
• n and m are independently 0, 1, 2, or 3;
• o and p are independently 0 or 1;
• M is —CR11═CR11a—, aryl, —O—, or —S—;
• R11 and R11a are independently hydrogen or C1-6-alkyl optionally substituted with aryl,
• E is
• —CONR12R13,
• wherein
• R12 is hydrogen or C1-6-alkyl optionally substituted with halogen, —CONR22R23, —N(R22)R23, —CF3, hydroxyl, C1-6-alkoxy, C1-6-alkoxy carbonyl, C1-6-alkylcarbonyloxy or aryl;
• R13 is
• wherein
• Q is —CH< or —N<,
• K and L are independently —CH2—, —CO—, —O—, —S—, —NR26— or a valence bond,
• where R26 is hydrogen or C1-6 alkyl, with the proviso that when Q is —CH<, at least one of K and L is —NR26—;
• t and u are independently 0, 1, 2, 3 or 4;
• R22 and R23 are independently hydrogen or C1-6 alkyl;
• v and w are independently 0, 1, 2 or 3;
• or a pharmaceutically acceptable salt thereof.