Neuropharmacological treatments of sleep-related breathing disorders
AssigneeThe Board of Trustees of the University of Illinois
InventorsMiodrag Radulovacki, David W. Carley
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Abstract
The present invention relates generally to pharmacological methods for the prevention or amelioration of sleep-related breathing disorders via administration of agents or combinations of agents that possess glutamate-related and/or glycine-related pharmacological activity or that modulate the release of either glutamate or glycine (or both) from nerve terminals with the central nervous system.
Claims6
A method of preventing or ameliorating sleep-related breathing disorder the method comprising administering to a patient in need thereof an effective amount of a glutamate receptor antagonist wherein the effects of the antagonist are exerted only in the central nervous system.
A method of preventing or ameliorating sleep-related breathing disorders the method comprising administering to a patient in need thereof an effective amount of an agent or combination of agents that inhibit the release of glutamate from nerve terminals within the central nervous system.
Dependencies are inferred from the claim text.