Weight promoting composition, method, and product

A method of promoting weight, comprising administering to the vomeronasal organ of a human a pregnane in an amount effective to promote weight by contact with the vomeronasal organ but ineffective to promote weight by systemic absorption into the circulatory system, where the pregnane has the formula:

• where
• R1=H, C1-4 alkyl, C1-4 alkanoyl, SO3H, or a salt thereof,
• R2=C1-4 alkyl,
• R3=H or methyl, and
• one or two non-adjacent members of a, b, c, and d are optional double bonds.