Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
AssigneeArtecel Sciences, Inc.
InventorsJeffrey Martin Gimble, Juan-Di Chang Halvorsen, William O. Wilkison
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Abstract
The invention relates to methods and compositions for the differentiation of stromal cells from adipose tissue into hematopoietic supporting stromal cells and myocytes of both the skeletal and smooth muscle type. The cells produced by the methods are useful in providing a source of fully differentiated and functional cells for research, transplantation and development of tissue engineering products for the treatment of human diseases and traumatic tissue injury repair.
Claims28
A non-naturally-occurring mixture of cells comprising an isolated extramedullary adipose tissue-derived stromal cell and a non-adipose derived cell capable of forming a blood cell.
A mixture of cells comprising an isolated extramedullary adipose tissue-derived stromal cell and a non-adipose derived cell capable of forming a blood cell.
A mixture of cells comprising an isolated human extramedullary adipose tissue-derived stromal cell and a non-adipose derived cell capable of forming a blood cell.
A mixture of cells comprising an isolated adult human extramedullary adipose tissue-derived stromal cell and a non-adipose derived cell capable of forming a blood cell.
A mixture of cells comprising an isolated adult human extramedullary adipose tissue-derived stromal cell and a non-adipose derived human cell capable of forming a blood cell.
Dependencies are inferred from the claim text.