Hybridization chamber for high density nucleic acid arrays
AssigneeCorning Incorporated
InventorsGeorge F. Lyman, Vic E. Myer, Christopher J. Wilson
Life of this patent
Estimating the term…
Abstract
The present invention provides a hybridization chamber that contains a built-in mechanism for saturating the air within the chamber when sealed thereby preventing drying of the liquid sample. The hybridization chamber is defined by matching top and bottom clam-shell like halves that, when brought together, are sealed by an o-ring and clamping device. The chamber is equipped with a liquid reservoir, the liquid from which will serve to saturate the volume of air sealed within the hybridization chamber. A saturated atmosphere within the chamber prevents evaporation of the sample.
Claims7
A device for use in performing hybridization assays comprising:
- a) a body having a chamber disposed therein including a chamber floor defined by a contained region for holding a liquid sample;
- and
- b) at least one well positioned within said chamber, the well adapted to retain liquid separately from said contained region and to allow controlled evaporation from the well;
- whereby said chamber is capable of being hermetically sealed from an external environment.
Dependencies are inferred from the claim text.