Polynucleotide encoding eimeria tenella cGMP dependent protein kinase
AssigneeMerck & Co., Inc.
InventorsAnne Gurnett, Paul A. Liberator, Robert Donald, Dennis Schmatz, Georgianna Harris, Sandra J. Rattray
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Abstract
Protozoal cyclic GMP dependent protein kinases have been isolated and cloned. These enzymes may be used in screening assays to identify potential antiprotozoal agents.
Claims9
An isolated polynucleotide comprising a sequence of nucleotides that encode a cGMP dependent protein kinase having an amino acid sequence as set forth in SEQ ID NO:11.
An isolated polynucleotide that encode a cGMP dependent protein kinase, wherein said polynucleotide comprises the nucleotide sequence as set forth in SEQ ID NO:
- 10.
A recombinant expression sequence comprising a polynucleotide sequence that encodes a cGMP dependent protein kinase, wherein the polynucleotide sequence comprises the sequence of nucleotides as set forth in SEQ ID NO:
- 10, and wherein said recombinant expression sequence expresses a cGMP dependent protein kinase in a host cell transformed or transfected with said recombinant expression sequence.
Dependencies are inferred from the claim text.