Nucleic acid encoding bovine extracellular rage binding protein (en-rage)
AssigneeThe Trustees of Columbia University in the City of New York
InventorsAnn Marie Schmidt, David Stern
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Abstract
The present invention provides for an isolated human EN-RAGE peptide. The present invention also provides for a method for determining whether a compound is capable of inhibiting the interaction of an EN-RAGE peptide with a RAGE peptide. The present invention also provides for a method for inhibiting inflammation in a subject which comprises administering to the subject a compound capable of interfering with the interaction between EN-RAGE peptide and receptor for advanced glycation endproduct (RAGE) in the subject thereby inhibiting inflammation in the subject.
Claims14
An isolated nucleic acid encoding a polypeptide comprising amino acids, the sequence of which is set forth in SEQ ID NO:2.
An isolated nucleic acid comprising nucleotides, the sequence of which is set forth in SEQ ID NO:1.
Dependencies are inferred from the claim text.