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AssigneeThe United States of America as represented by the Secretary of the Army
InventorsJohn P. Petrali, Robert Kwai Kan, Tracey A. Hamilton, Susan B. Oglesby-Megee
Estimating the term…
A method is described of viewing a single tissue sample with a light microscope and an electron microscope. A tissue sample is cryopreserved, cryo sectioned and then floated in a cryoprotectant solution on a surface of a glass slide or in a well and is viewed by light microscopy. The step of floating the tissue sample does not destroy said tissue sample for subsequent electron microscope viewing. The same tissue sample is then prepared by conventional ultrastructural processing for viewing by electron microscopy. The data from the light microscope and electron microscope images of selected sites of the same tissue sample can be compared and analyzed.
A method of viewing a single tissue sample with a light microscope and an electron microscope comprising:
A method of studying the pathogenesis of vesicants on skin that preserves a skin basement membrane zone of said skin and does not compromise zone function comprising:
A method of studying the pathogenesis of vesicants on skin that preserves a skin basement membrane zone of said skin and does not compromise zone function comprising:
A specimen suitable for viewing by both a light microscope and an electron microscope comprising:
Dependencies are inferred from the claim text.