Schizophrenia associated gene, proteins and biallelic markers
AssigneeGenset S.A.
InventorsDaniel Cohen, Marta Blumenfeld, Ilya Chumakov, Lydie Bougueleret, Laurent Essioux
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Abstract
The invention concerns the human g35030 gene, polynucleotides, polypeptides biallelic markers, and human chromosome 13q31-q33 biallelic markers. The invention also concerns the association established between schizophrenia and bipolar disorder and the biallelic markers and the g35030 gene and nucleotide sequences. The invention provides means to identify compounds useful in the treatment of schizophrenia, bipolar disorder and related diseases, means to determine the predisposition of individuals to said disease as well as means for the disease diagnosis and prognosis.
Claims40
An isolated, purified and recombinant polynucleotide comprising a contiguous span of at least 30 nucleotides between nucleotide positions 199122 to 249803 of SEQ ID NO:1, wherein said contiguous span comprises the biallelic marker shown as A56.
Dependencies are inferred from the claim text.