Synergistic mixtures of garlic and lycopene for preventing LDL oxidation

A synergistic hypercholesterolemia therapeutic agent which contains lycopene and garlic as effective ingredients, and optionally further comprising at least one of dietary components, additives, excipients, binding agents, coatings and preservatives.

A method for inhibiting development or treatment of atherosclerosis in a mammal, said method comprising

• administering an effective amount of a synergistic mixture lycopene and garlic to said mammal in need of such inhibiting or treatment, and wherein said mixture optionally also includes at least one of dietary components, additives, excipients, binding agents, coatings, and preservatives.

A method for inhibiting development of or treatment of atherosclerosis in a mammal, said method comprising

• administering an effective amount of a synergistic mixture lycopene and garlic to said mammal in need of such inhibiting or treatment, and wherein said mixture optionally also includes at least one of dietary components, additives, excipients, binding agents, coatings, and preservatives,
• wherein the lycopene is contained in tomato oleoresin.

A method for inhibiting development of or treatment of atherosclerosis in a mammal, said method comprising

• administering an effective amount of a synergistic mixture lycopene and garlic to said mammal in need of such inhibiting or treatment, and wherein said mixture optionally also includes at least one of dietary components, additives, excipients, binding agents, coatings, and preservatives,
• wherein said lycopene comprises synthetic lycopene.

A method for inhibiting development of or treatment of atherosclerosis in a mammal, said method comprising

• administering an effective amount of a synergistic mixture lycopene and garlic to said mammal in need of such inhibiting or treatment, and wherein said mixture optionally also includes at least one of dietary components, additives, excipients, binding agents, coatings, and preservatives,
• wherein the garlic is selected from the group consisting of whole garlic, allicin, garlic powder, non-polar solvent extracts of fresh crushed garlic, aged deodorized garlic extract, and mixtures of these.

A method for inhibiting development of or treatment of atherosclerosis in a mammal, said method comprising

• administering an effective amount of a synergistic mixture lycopene and garlic to said mammal in need of such inhibiting or treatment, and wherein said mixture optionally also includes at least one of dietary components, additives, excipients, binding agents, coatings, and preservatives,
• wherein the relative parts by weight of garlic to lycopene is from 10,000 to 1 to 1 to 10,000.

A method for inhibiting development of or treatment of atherosclerosis in a mammal, said method comprising

• administering an effective amount of a synergistic mixture lycopene and garlic to said mammal in need of such inhibiting or treatment, and wherein said mixture optionally also includes at least one of dietary components, additives, excipients, binding agents, coatings, and preservatives,
• wherein the lycopene and garlic mixture is contained in a matrix selected from the group consisting of tablets, caplets, vegecaps, and hard shell gelatin capsules.

A method for blocking the oxidation of LDL in serum which comprises contacting said serum with a synergistic composition containing lycopene and garlic, and wherein said composition optionally also comprises at least one of dietary components, additives, excipients, binding agents, coatings, and preservatives.