Radioactive intraluminal endovascular prothesis and method for the treatment of aneurysms

A method for treatment of an intracranial aneurysm which is in the form of an aneurysmal sac, said method comprising:

• providing an endovascular device that emits radiation at a selected radiation dose and at a selected low dose rate;
• and
• placing the endovascular device into the aneurysmal sac to irradiate at least a portion of the aneurysmal sac with radiation at the collective radiation dose and at the low dose rate for the sufficient period of time sufficient to cause an increase in the rate of at least one of cell proliferation, cellular adhesion and thrombus formation in the aneurysmal sac to affect accelerated repair of the intracranial aneurysm.

A method for treatment of an intracranial aneurysm which is in the form of an aneurysmal sac, said method comprising:

• providing an endovascular device having a radioactive isotope selected to emit radiation at a low dose rate;
• and
• placing and anchoring the endovascular device into the aneurysmal sac for a period of time sufficient to expose at least a portion of the aneurysmal sac to the radiation at a selected radiation dose and at the selected low dose rate to cause an increase in the rate of at least one of cell proliferation, cellular adhesion and thrombus formation in the aneurysmal sac to affect accelerated repair of the intracranial aneurysm.

A method of fabricating an endovascular device for the treatment of an intracranial aneurysm which is in the form of an aneurysmal sac, said method comprising:

• providing an endovascular device for the placement and anchoring into the aneurysmal sac;
• and
• causing the endovascular device to become radioactive to emit radiation at a selected radiation dose and at a selected low dose rate such that exposure of at least a portion of the aneurysmal sac to the radiation for a sufficient period of time causes an increase in the rate of at least one of cell proliferation, cellular adhesion and thrombus formation in the aneurysmal sac to affect accelerated repair of the intracranial aneurysm.