Density enhanced protein tyrosine phosphatases
AssigneeCold Spring Harbor Laboratory
InventorsNicholas K. Tonks, Arne Ostman
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Abstract
Novel Type III density enhanced protein tyrosine phosphatases are disclosed and exemplified by human DEP-1 enzyme. Polynucleotides encoding huDEP-1 are disclosed, along with methods and materials for production of the same by recombinant procedures. Binding molecules specific for DEP-1 are also disclosed as useful for modulating the biological activities of DEP-1.
Claims2
An isolated human Type III density enhanced protein-1 tyrosine phosphatase polypeptide (huDEP-1) comprising an amino acid sequence set forth in SEQ ID NO:2.
An isolated polypeptide, said polypeptide being immunologically reactive with an antibody that specifically binds to a human Type III density enhanced protein-1 tyrosine phosphatase polypeptide (huDEP-1) polypeptide comprising an amino acid sequence set forth in SEQ ID NO:2.
Dependencies are inferred from the claim text.