Compounds for altering mitochondrial function and cellular responses

A compound having the structure:

• or a stereoisomer, prodrug or pharmaceutically acceptable salt thereof,
• wherein:
• A is a direct bond, alkyldiyl, substituted alkyldiyl, —O-(alkyldiyl)-, —O-(substituted alkyldiyl)-, -(alkyldiyl)—O—, -(substituted alkyldiyl)—O—, —N(R′)-(alkyldiyl)-, —N(R′)-(substituted alkyldiyl)-, -(alkyldiyl)-N(R′)—, -(substituted alkyldiyl)-N(R′)—, heterocyclediyl, substituted heterocyclediyl, heterocyclealkyldiyl or substituted heterocyclealkyldiyl, wherein R′ is hydrogen or alkyl;
• R1 is hydroxy, alkoxy, aryloxy, arylalkyloxy, amino, or mono- or di-alkylamino;
• R2 is hydrogen, alkyl, substituted alky, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heterocycle, substituted heterocycle, heterocyclealkyl or substituted heterocyclealkyl;
• and
• R3 is alkyl, substituted alky, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heterocycle, substituted heterocycle, heterocyclealkyl or substituted heterocyclealkyl.