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US 6,552,056 B2Granted
Isothiazolecarboxamides and their use as microbicides
AssigneeNihon Bayer Agrochem K.K.
InventorsLutz Assmann, Yoshinori Kitagawa, Koichi Ishikawa, Daiei Yamazaki, Haruko Sawada, Yasuo Araki, Haruhiko Sakuma, Taro Kinbara, Kinya Imanishi
Life of this patent
Estimating the term…
Abstract
Isothiazolecarboxamides of the formula: wherein X, Y, R1, R2, R3 and R4 have the meanings given in the specification, may be used as microbicides.
Claims13
An isothiazolecarboxamide of the formula
- wherein
- X represents fluoro, chloro, bromo, methyl, ethyl or trifluoromethyl,
- Y represents a hydrogen atom, fluoro, chloro, bromo, cyano, methoxycarbonyl or ethoxycarbonyl,
- R1 represents a hydrogen atom,
- R2 represents a hydrogen atom or methyl,
- R4 represents methyl or ethyl,
- R3 represents a hydrogen atom, C1-12 alkyl, C3-6 cycloalkyl, C2-6 alkenyl which may be substituted with phenyl, or
- R3 represents C5-6 cycloalkenyl, C7 bicycloalkenyl, C1-2 haloalkyl, or
- R3 represents C1-4 alkyl, which is substituted with 1 or 2 substituents selected from the group consisting of hydroxy, C1-4 alkoxy, mercapto, C1-4 alkylthio, C1-4 alkylsulfinyl, C1-4 alkylsulfonyl, phenyl and a 5-membered heterocyclic ring having 1-3 nitrogen atoms which may be benzo-condensed, or
- R3 represents phenyl, which may be substituted with 1 to 4 groups selected from the group consisting of C1-4 alkyl, halogen, C1-4 haloalkyl, C1-4 haloalkoxy, nitro, cyano, C1-4 alkoxy, benzyloxy, phenoxy, C1-4 alkylenedioxy, C1-4 alkylthio, di-C1-4 alkyl-amino and phenyl, or
- R3 represents naphtyl, which may be substituted with methoxy, or
- R3 represents a 5- or 6-membered heterocyclic group, which has 1 to 3 heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, which heterocyclic groups may be benzo-condensed and may be substituted with 1 to 3 substituents selected from the group consisting of C1-4 alkyl, halogen C1-4 alkoxy, C1-4 alkylthio and nitro,
- or
- R2 and R3, together with the carbon atom to which they are bonded, form a C5-6 cycloalkyl, which may be substituted with 1 or 2 methyl groups, or
- R2 and R3, together with the carbon atom to which they are bonded, form a 5- or 6-membered heterocyclic ring, which comprises one nitrogen atom and which may be substituted with 1 or 2 methyl groups, or
- R2 and R3, together with the carbon atom to which they are bonded, form a group of the formula
- C═CH—R5, in which
- R5 represents a hydrogen atom, methyl or ethyl,
- or
- R3 and R4, together with the carbon atom and the carboxyl group to which they are bonded, form a 5- or 6-membered heterocyclic ring having one ring-constituting oxygen atom and being substituted with one oxo group,
- with the proviso, however, that
- R3 does not represent isopropyl,
- if
- X and Y represent chloro, and
- R2 represents a hydrogen atom.
22 more elements
Dependencies are inferred from the claim text.