Back to results
US 6,552,032 B2Granted
Opiate compounds, methods of making and methods of use
AssigneeResearch Triangle Institute
InventorsFrank I. Carroll, James B. Thomas, S. Wayne Mascarella
Life of this patent
Estimating the term…
Abstract
The present application relates to novel opioid receptor antagonists and agonists, methods of making these compounds, and methods of use thereof.
Claims6
A compound represented by formula (II):
- R1 is an alkyl group or aralkyl group;
- and
- R3, R4, R5, R6 are each, independently, hydrogen, an alkyl group, —OH, —NH2, —NHR, —N(R)2, halogen, —OR, —CF3, —CN, —NO2, or —NHC(O)R, wherein when any of R3, R4, R5, or R6 is N(R)2 the R groups may, together, form a cyclic alkyl group;
- each R is, independently, an alkyl group, an aryl group, or an alkaryl group;
- and
- R7 is hydrogen or an alkyl group,
- or a pharmaceutically acceptable salt thereof.
4 more elements
Dependencies are inferred from the claim text.